Inspire Therapy
What is Inspire Therapy?
Inspire® therapy is a mask-free1 solution for people with obstructive sleep apnea who have tried and struggled with CPAP.
How Inspire Therapy Works
The system includes three components:
1. The Implantable Device
- Placed under the skin during a minor outpatient procedure.
- Placed under the skin during a minor outpatient procedure.
2. The Patient Remote
- Turn therapy on before bed and off when you wake up. Adjust stimulation strength as needed.
3. The Inspire Sleep App
- Track sleep quality, therapy usage, and share data with your care team.
Key Benefits:
Proven Effectiveness:
Improved Quality of Life
94% of patients recommend Inspire.
Silent Nights
90% of bed partners report no or soft snoring
Convenience
Who Qualifies for Inspire Therapy?
Inspire is ideal for adults with moderate to severe OSA who:
1. Diagnosis & Severity
- Confirmed OSA diagnosis (Apnea-Hypopnea Index/AHI 15-100).
- Not effectively treated by CPAP or intolerant to CPAP therapy.
2. Health Criteria
- BMI ≤ 40 (no significant weight loss required).
- No complete concentric collapse of the soft palate (confirmed via sleep endoscopy).
3. Lifestyle & Medical History
- Not candidates for traditional airway surgeries (e.g., UPPP).
- Free of neuromuscular diseases or conditions affecting nerve function.
Pediatric Use: Inspire is also FDA-approved for children aged 13+ with Down Syndrome and OSA.
The Inspire Therapy Process: Step-by-Step
- Initial Consultation
- Sleep Study Review: Our team evaluates your OSA severity and CPAP usage history.
- Drug-Induced Sleep Endoscopy (DISE): A 15-minute procedure to assess airway collapse patterns.
- Pre-Screening: Confirm BMI, medical history, and eligibility.
- Implant Procedure
- Outpatient Surgery: Performed under general anesthesia (≈2 hours).
- Device Placement:
- A small generator is implanted near the collarbone.
- Two leads are connected to the hypoglossal nerve and a breathing sensor.
- Recovery: Most patients resume light activities within 24-48 hours.
- Activation & Customization (4 Weeks Post-Surgery)
- In-Office Setup: Our specialists activate the device and tailor stimulation settings to your comfort.
- Remote Training: Learn to use the handheld remote and app.
- Long-Term Follow-Up
- 1-Month Check-In: Optimize therapy settings.
- Annual Visits: Ensure device function and sleep improvement.

Safety & Effectiveness
FDA-Approved
Risks
Success Rates
Over 90% of patients achieve significant reduction in OSA symptoms.
Insurance & Cost
Coverage
Financial Assistance
Our team helps verify benefits, navigate prior authorization, and explore payment plans.
Why Choose Premier Head & Neck Surgery?
Certified Inspire Specialists
Comprehensive Care
Proven Outcomes
98% patient satisfaction rate for Inspire Therapy at PHNS.
Frequently Asked Questions
Most patients feel only mild discomfort post-surgery. Stimulation during sleep is typically described as a gentle tingling.
10-11 years
No—Inspire includes a travel card to show security if needed.
1. Inspire Therapy vs. CPAP
Factor | Inspire Therapy | CPAP |
---|---|---|
Comfort | No mask or tubing; uses a discreet implant. | Requires wearing a mask and hose nightly. |
Compliance | 90% long-term adherence (no daily discomfort). | 30-60% of patients struggle with consistent use. |
Effectiveness | Reduces AHI by ~79%; treats moderate to severe OSA. | Highly effective when used correctly, but only if worn. |
Noise | Silent operation. | Machine noise may disturb sleep for some. |
Portability | Easy travel with a handheld remote. | Requires carrying a machine and accessories. |
Best For | CPAP-intolerant patients seeking a permanent solution. | Patients who tolerate masks and prefer non-surgical options. |
Key Takeaway: Inspire is ideal if CPAP feels restrictive or ineffective, offering similar benefits without nightly equipment.
2. Inspire Therapy vs. Oral Appliances
Factor | Inspire Therapy | Oral Appliances |
---|---|---|
Mechanism | Implant stimulates airway muscles. | Repositions the jaw to prevent airway collapse. |
Effectiveness | Effective for moderate to severe OSA. | Best for mild to moderate OSA; less reliable for severe cases. |
Comfort | No oral discomfort; fully internal. | May cause jaw pain, tooth shifting, or dry mouth. |
Durability | Long-term solution (10+ years). | Requires replacement every 1-3 years. |
Adjustability | Settings customized remotely via app. | Limited adjustments; requires dental visits. |
Best For | Patients needing a robust, hands-free solution. | Patients needing a robust, hands-free solution. |
Key Takeaway: Inspire provides stronger, more reliable results for moderate to severe OSA, while oral appliances suit milder cases.
3. Inspire Therapy vs. Upper Airway Surgery (e.g., UPPP)
Factor | Inspire Therapy | Upper Airway Surgery |
---|---|---|
Invasiveness | Minimally invasive outpatient procedure. | Often requires removing tissue; longer recovery. |
Recovery Time | 1-2 days for light activities. 2-4 weeks of downtime. | 2-4 weeks of downtime |
Reversibility | Fully reversible; device can be removed. | Fully reversible; device can be removed. |
Success Rate | ~90% achieve significant AHI reduction. | 40-60% success rate, depending on anatomy. |
Risks | Low risk of infection or discomfort | Higher risk of pain, bleeding, or swallowing changes |
Best For | Patients seeking predictable results with fewer risks | Patients with specific anatomical issues (e.g., enlarged tonsils) |
Key Takeaway: Inspire offers a safer, reversible alternative to traditional surgery with higher success rates for most patients.
Inspire Therapy vs. Lifestyle Modifications
Factor | Inspire Therapy | Lifestyle Changes |
---|---|---|
Mechanism | Directly addresses airway collapse during sleep. | Directly addresses airway collapse during sleep. |
Speed of Results | Immediate improvement post-activation. | Gradual results (months to years). |
Effectiveness | Treats root cause of OSA. | Helpful but rarely curative for moderate-severe OSA. |
Sustainability | Long-term solution with minimal effort. | Requires lifelong commitment to diet/exercise. |
Best For | Patients needing rapid, reliable symptom relief. | Complementary to Inspire or mild OSA cases. |
Key Takeaway: Inspire provides definitive treatment, while lifestyle changes work best as supportive measures.
Why Inspire Stands Out
- Only FDA-approved implantable OSA treatment with over a decade of clinical data.
- Combines the benefits of CPAP effectiveness and surgical permanence without major risks.
- Fully adjustable to match your evolving needs.
- Reversible, unlike airway-altering surgeries.
Which Treatment is Right for You?
Choose Inspire if:
- You have moderate to severe OSA.
- CPAP feels uncomfortable or ineffective.
- You want a low-risk, long-term solution without daily effort.
-
- You have mild OSA or anatomical issues better treated surgically.
- You prefer non-implant options (e.g., CPAP or oral appliances).
Still Unsure?
Schedule a consultation with our Inspire-certified specialists at Premier Head & Neck Surgery. We’ll review your sleep study, anatomy, and goals to recommend the best treatment for you.